Threshold effect regression analysis on four routine markers (serum CRP, ESR, synovial WBC, and synovial PMN%) for chronic PJI diagnosis among the non‐IA population revealed different results, with three having new cut‐offs: 13.5 mg/L, 4100/μL and 70% for serum CRP, synovial WBC and synovial PMN%, respectively (Table 2). The gene discussed is CRP; the disease is juvenile polyposis syndrome.