After adjusting for the variables of gender, lymphatic metastasis, tumour size, TNM stage and differentiation, no statistical significance was found between the SNPs in MLH3, hOGG1 genes and overall survival in the univariate analysis, while three SNPs of ERCC1 including the rs735482, rs2336219 and rs3212986 exhibited different survival indices among different genotypes. The gene discussed is OGG1; the disease is neoplasm.