The ABO gene is located on chromosome for specific glycosyltransferases which is finally converted into A or B antigen.[10–12] O gene encodes a nonfunctional glycosyltransferase and O blood group was associated with the absence of lymph node metastasis in urinary carcinoma patients.[13,14] Based on those studies, the ABO blood type and rhesus factor has emerged as an inexpensive, readily available markers that is associated with prognosis of patients with various malignancies including bladder, renal and pancreatic cancer.[13–16]. The gene discussed is ABO; the disease is familial pancreatic carcinoma.