As shown in Table 2, TYROBP was an independent prognostic factor for OS in patients of male sex (HR = 0.528, P = .016), age below 18 years (HR = 0.647, P = .012), metastasis (HR = 0.566, P = .043), and tumor site at leg/foot (HR = 0.585, P = .002). This evidence concerns the gene TYROBP and neoplasm.