TP53 and neoplasm: PNI is statistically different in the tumor grade (P < .001), T stage (P < .001), N stage (P < .001), p53 (P = .032), which is not significantly different from gender (P = .123), age (P = .750), mucous glands cancer (P = .427), tumor size (P = .351), and EGFR (P = .227) (Table 1).