This is similar to the study that found a positive correlation between BMI and sUA in healthy Chinese people and revealed that the related risk of sUA levels and obesity was greater in women.[20] Another Thailand research also reported high sUA levels were correlated with a greater risk of obesity in women.[21] Women with obesity, according to Kim et al, had a greater risk of severe hyperuricemia than males.[10,11] Several studies[22–24] reported that possible mechanisms contained hormonal impact or sex variations in insulin sensitivity and body fat composition. The gene discussed is INS; the disease is obesity due to melanocortin 4 receptor deficiency.