As for SNORD63, a previous study reported that SNORD63 was greatly upregulated in urinary sediment and SNORD96A elevated in plasma could act as a noninvasive diagnostic biomarker for clear cell renal cell carcinoma.[28] Recently, Liu et al[27] identified 15 snoRNAs that were significantly related to sarcoma prognosis and constructed a prognostic signature based on 4 prognostic snoRNA (U3, SNORA73B, SNORD46, and SNORA26) expression values. This evidence concerns the gene SNORD63 and clear cell renal carcinoma.