Additionally, we performed GSEA and found that high-risk patients were not only enriched in pro-cancer-related pathways, such as epithelial mesenchymal transition, hypoxia, and KRAS signaling, but also enriched in immune related pathways, such as inflammatory response, cytokine-cytokine receptor interaction, chemokine signaling pathway and focal adhesion (Fig. 5E and F). Here, KRAS is linked to cancer.