In glioblastoma (GBM) or low-grade glioma (LGG) with TP53 mutations, 3137 and 3648 genes were significantly differentially expressed in the KIT down-regulation GBM or LGG group compared with KIT up-regulation GBM or LGG group (Additional file 1: Fig. S4D). The gene discussed is KIT; the disease is low grade glioma.