In consistency with our ChIP-seq results, the size exclusion experiment has shown significant overlap between ASXL2/3 and MBD6 (Additional file 2: Fig. S5K), indicating that there is a stronger co-function between ASXL2/3 and MBD6 versus ASXL1/MBD6 in SCLC cells. Here, ASXL1 is linked to small cell lung carcinoma.