After multivariate logistic regression analysis, the significant risk factors, including AFP ≥ 400 kU/L (OR 0.072, P < 0.001), tumor diameter (TD) ≥ 5 cm (OR 0.400, P = 0.041), and TNM stage III–IV (OR 0.094, P < 0.001), were selected to construct a logistic regression model (Table 4). The gene discussed is AFP; the disease is neoplasm.