CD4 and infection: These populations seemed dynamic over the course of infection, with chronic stages associated with a 1.27- and 1.61-fold increase in the abundance of Cd4+ T cells compared to other subclusters (23.64%, 30.21%, and 38.1% in naïve, 25dpi, and 45dpi, respectively) (Fig. 4B and D), consistent with previous reports5,42.