While some studies associate Lp(a) independently with cIMT and plaque development, other studies have not shown such an association.14, 15, 16, 17, 18 Furthermore, given the important role of Lp(a) in the development of cardiovascular diseases, the present study aimed to explore the association between Lp(a) levels and subclinical carotid atherosclerosis measured as cIMT as well as the presence of carotid plaques in asymptomatic individuals. The gene discussed is LPA; the disease is carotid atherosclerosis.