Secondly, patients who were not started on ART because of high CD4 count were associated with low retention to care and associated with high mortality and morbidity due to AIDS progression [32,33].Therefore, with the revised eligiability guidelines, which recommended ART initiation regardless of the clinical stage, we believe studies including adoelscents on ART post the 2010 guidelines will therefore present comparable barriers to ART. The gene discussed is CD4; the disease is AIDS.