For cases 49, 51 (Table 3), 57, 60–63 (Table 4) our temptative diagnosis was autoantibody-negative T1D; however, we can not exclude an inherited (Table 3) or spontaneous (Table 4) small HNF1A/HNF4A deletion or pathogenic variant(s) in regulatory regions of these genes. This evidence concerns the gene HNF4A and type 1 diabetes mellitus.