None had a history of negative pregnancy outcome or pregnancy complications (gestational diabetes, preeclampsia, eclampsia, Hemolysis Elevated Liver Enzymes and Low Platelets [HELLP] syndrome); no antiphospholipid tests (LAC or aCL antibody) or disease severity scores (PGA or SDI) were available for these two cases. The gene discussed is ACLY; the disease is gestational diabetes.