PML and sarcoma: The exact components of intranuclear inclusions are still unknown; previous studies have demonstrated that many nonspecific proteins, such as glucocorticoid receptor, promyelocytic leukemia protein (PML), histone deacetylase 4 (HDAC4), small ubiquitin modifier-1 (Sumo-1), fused in sarcoma, optineurin, myosin 6, heat shock protein 90, and dynamin-1, were found to be present in intranuclear inclusions by immunostaining (McFadden et al., 2005; Takahashi-Fujigasaki et al., 2006; Pountney et al., 2008; Nakamura et al., 2014; Nakano et al., 2017).