FANCM and anemia (phenotype): We repeated the analysis on the HR’s network extended by adding the pathways of FANCM gene (Fanconi Anaemia Group M Protein), obtained from Pathways Commons (Pathways Commons, 2022) given its important role in genome duplication, repair mechanisms and its involvement in the development of Fanconi anaemia, which several studies report to be a syndrome related to cancer predisposition (Deans and West, 2009; Xue et al., 2015; Bhattacharjee and Nandi, 2017; Pan et al., 2017; Wang et al., 2018).