SCN5A and cardiomyopathy: CTG nucleotide expansion in myocytes leads to hairpin RNA structures that bindsplicing factors in cellular nuclei resulting in abnormal splicing of the TNNT2and SCN5A genes which, in turn, is thought to contribute to cardiomyopathy [12].Cardiomyopathy associated with DM1 and DM2 progresses with age; as such regularechocardiography with strain imaging is a class IC recommendation by the AmericanHeart Association (AHA) to track progression [6, 51].