MOG and optic neuritis: There are few cases of bilateral optic neuritis during COVID-19 infection, both of which report positive anti-myelin oligodendrocyte glycoprotein antibodies, which recommend the immune-mediated demyelination in the optic nerve as the pathogenesis; however, the virus could not be detected in the cerebrospinal fluid (CSF) or on magnetic resonance imaging (MRI) results, which rejects the direct effect of the virus (65, 66).