The high expression of GSDME showed poor prognosis of CLL in respect of both OS (HR = 3.4918, p < 0.001) and TTFT (HR = 3.201, p < 0.001), and the high expression of NLRP3 and PLCG1 displayed superior prognosis of CLL (Figures 5A–C). Here, PLCG1 is linked to B-cell chronic lymphocytic leukemia.