Further exploration of the prognostic value of ISG20 revealed that higher expression was associated with a shorter OS in ACC, DLBC, LAML (acute myeloid leukemia), LGG (lower grade glioma), and UVM (uveal melanoma) (Figures 3C–G), but with a long OS in CESC, OV (ovarian serous cystadenocarcinoma), and SKCM (Figures 3H–J). This evidence concerns the gene ISG20 and central nervous system cancer.