When only considering patients with the Pi∗MM (n = 1,030) and the Pi∗MZ (n = 39; i.e., the common heterozygous form of AAT-related liver disease) genotypes, the Pi∗MZ genotype was associated with liver-related death or the requirement for liver transplantation in univariable analysis (SHR 1.88; 95% CI 1.20-2.95; p = 0.006; Fig. S2). Here, SERPINA1 is linked to liver disorder.