Because one of our COVID-19 patients (unpublished case report) with progressively severe cough and shortness of breath, with deteriorating general condition (the patient was terrified of dying), became totally asymptomatic within seven days of IBDV treatment (7 × 106 IU in total), it is tempting to speculate that the IBDV R903/78 drug candidate with its IFN activation properties would be promising as anti-SARS-CoV-2 therapy even in severe COVID-19 patients. Here, IFNA1 is linked to COVID-19.