Fibrosis is related to a variety of signaling pathways, such as TGFβ/SMAD signaling pathway, integrin signaling pathway, MAPK signaling pathway, ROCK Rho‐related signaling pathway, etc. Current studies have shown that Hippo/YAP can interact with proteins to regulate vascular smooth muscle proliferation.43 The gene discussed is TGFB1; the disease is fibrosis.