As shown in Figure 6A, the KEGG biological pathways significantly enriched in the DTE group were as follows: Retinol metabolism, Chemical carcinogenesis, Arachidonic acid metabolism, PPAR signaling pathway, Drug metabolism enzymes, Staphylococcus aureus infection, Drug metabolism-cytochrome P450, Complement and coagulation cascades, Amoebiasis, atherosclerosis, Glutathione metabolism, and Oxidative phosphorylation. The gene discussed is PPARA; the disease is amebiasis.