As shown in Figure 6B, the KEGG biological pathways significantly enriched in the MET group were as follows: Complement and coagulation cascades, Staphylococcus aureus infection, Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Systemic lupus erythematosus, Cell adhesion molecule, Amoebiasis, IL-17 signaling pathway, Chemokine signaling pathway, Glutathione metabolism, Primary immunodeficiency, Arachidonic acid metabolism. This evidence concerns the gene IL17A and amebiasis.