STAT3 and neoplasm: Here, the IL‐6/JAK/STAT3 pathway was downregulated on Day 7 (NES = −1.65, FDR = 0.003) and Day 14 (NES = −1.63, FDR = 0.003), suggesting that modulation of this pathway is partially responsible for the observed NTP effects on tumor kinetics and mouse survival (Figure 2g).