Compared to the patients without newly detected AF (Table 1), the patients with AF were significantly older (80 vs. 71 years; p < 0.001), included more females (48.4 vs. 34.7%; p = 0.028), had a higher rate of ESUS (46.9 vs. 22.2%; p < 0.001), lower incidence of diabetes mellitus (31.3 vs. 47.8%; p = 0.011), higher incidence of receiving recombinant tissue plasminogen activator (rt-PA) treatment (12.5 vs. 4.0%; p = 0.002), and higher incidence of congestive heart failure (7.8 vs. 1.3%; p < 0.001). The gene discussed is PLAT; the disease is diabetes mellitus.