GRB2 and type 2 diabetes mellitus: Meaningfully, IL-6 (median 1.34 vs 2.07 vs 2.91pg/ml, P < 0.001) and serum GRB2 levels (median 3.05 vs 4.40 vs 7.09, P < 0.001ng/ml) (Figure 1) were significantly higher in the T2DM group than the healthy population and further increased in the CAS patients (P<0.001) (Table 2).