GRB2 and type 2 diabetes mellitus: In addition, the area under the ROC curve was 0.80 (95%CI: 0.7291-0.8613, P<0.001), the best diagnostic threshold was 4.59 ng/ml, the sensitivity was 83.58%, and the specificity was 70.59%, indicating that serum GRB2 has a high diagnostic value for T2DM with CAS (Figure 4).