The results showed that NSCLC patients with higher expression levels of CDC6 [HR = 1.88 (1.65–2.14), p < 1e-16], KIAA0101 [HR = 1.71 (1.5–1.94), p = 2.2e-16], CDC20 [HR = 1.82 (1.6–2.07), p < 1e-16], BUB1B [HR = 1.7 (1.5–1.94), p = 2.2e-16], CCNA2 [HR = 1.76 (1.55–2), p < 1e-16], NCAPG [HR = 1.59 (1.4–1.8), p = 8.8e-13], KIF11 [HR = 1.52 (1.34–1.73), p = 1.1e-10], BUB1 [HR = 1.83 (1.61–2.08), p < 1e-16], CDK1 [HR = 1.4 (1.23–1.59), p = 2.3e-07] had worse OS (Figure 5A). Here, PCLAF is linked to non-small cell lung carcinoma.