Hu et al. (2019)analyzed cerebrospinal fluid samples from AD, MS, PD, and DLB patients and found that four cytokines (IL-10, IP-10, IL-8, and TNF-α) related to innate immunity and subtypes of helper T cells (Th1, Th2, and Th17) have much greater levels of expression in the cerebral fluid of patients with degenerative disorders than healthy people. Here, TNF is linked to myeloid sarcoma.