Nazari PMS et al. explored the intercorrelation between intratumoral Pdpn expression and the isocitrate dehydrogenase 1 (IDH 1) mutation, and their mutual impact on VTE development in brain tumors, and found the risk of VTE in patients with IDH1 wild-type tumors was strongly correlated to Pdpn expression levels (Mir Seyed Nazari et al., 2018). The gene discussed is PDPN; the disease is brain neoplasm.