In addition, genome editing technology as a new technology is now widely used in treating autoimmune diseases (Mohammadzadeh et al., 2020), for example, by genome editing IL-37 can enhance mesenchymal stem cells (MSCs) thus providing a new and reliable approach for the treatment of SLE (Xu et al., 2020b). This evidence concerns the gene IL37 and systemic lupus erythematosus.