Eighty patients showed glioblastoma (GBM)-like features: IDH1 and 2 wild types (wt) and imbalance of chromosome 7 and chromosome 10q loss of heterozygosity, or telomerase reverse transcriptase (TERT) promoter mutation, or epidermal growth factor receptor (EGFR) amplification (40). This evidence concerns the gene TERT and glioblastoma.