In a further publication, protein interaction data showed that PRPF6, 8 and 31 interact with many proteins involved in processes beyond splicing, including translation, mRNA stability, mRNA export and DNA damage response (Boldt et al., 2016), further suggestion that these proteins have roles in addition to splicing and that it may be dysregulation of these functions which underlie RP. The gene discussed is PRPF6; the disease is retinitis pigmentosa 1.