Homeobox C6 (HOXC6) is a transcription factor that is implicated in the malignant progression of several cancers, including gastric cancer (Liu et al., 2020a; Lin et al., 2020), hepatocellular carcinoma (Li et al., 2018), colon carcinoma (Liu et al., 2020b). Here, HOXC6 is linked to hepatocellular carcinoma.