Liang et al. (Tao et al., 2022) showed that inhibition of the PI3K/Akt signaling pathway can upregulate the expression of miR-205-5p and that miR-205-5p can inhibit the production of VEGF-A in breast cancer cells as well as tumor angiogenesis and metastasis. Here, AKT1 is linked to breast carcinoma.