As SLC2A12 is known to code for a glucose transporter (Wood et al., 2003), further studies on the role of the SLC2A12 and the correlation with metabolic regulations in TM can provide deeper insights into the relationship between hyperglycemia and POAG (Zhou et al., 2014; Hymowitz et al., 2016). This evidence concerns the gene SLC2A12 and Hyperglycemia.