Recently, the RNA-binding motif, single-stranded-interacting protein 1 (RBMS1), an RNA-binding protein, was found to directly interact with the translation initiation factor eIF3d, connecting the 3′- and 5′-UTRs of SLC7A11. RBMS1 ablation can sensitize radioresistant lung cancer cells to radiation by inhibiting SLC7A11 translation and inducing ferroptosis (Zhang et al., 2021c). Here, SLC7A11 is linked to lung cancer.