SLC7A11 and lung carcinoma: Recently, the RNA-binding motif, single-stranded-interacting protein 1 (RBMS1), an RNA-binding protein, was found to directly interact with the translation initiation factor eIF3d, connecting the 3′- and 5′-UTRs of SLC7A11. RBMS1 ablation can sensitize radioresistant lung cancer cells to radiation by inhibiting SLC7A11 translation and inducing ferroptosis (Zhang et al., 2021c).