ERBB4 and Anxiety: Compared to DSS-treated SiHo WT mice, DSS-treated CoHo WT mice showed a trend toward increased plasma corticosterone level and reduced ErbB4 expression in the hypothalamus, indicating that gut microbiota alteration might be involved in the HPA axis hyperactivity and the anxiety-like behaviors through regulating the ErbB4 expression in the hypothalamus.