This study suggests that hsa_circ_0003600-hsa-miR-4741-BIRC5/OIP5/AR regulatory axis may also be one of the potential mechanisms of IDD, but there is a lack of research support, as does the hsa_circ_0002702-hsa-miR-3158-5p-IGF1/AR regulatory axis, which are the direction and goal of our future research. This evidence concerns the gene BIRC5 and intervertebral disk degenerative disorder.