IL1B and Alzheimer disease: In order to evaluate the effect of currant diet on neuroinflammation, another process that contributes to AD pathogenesis, we measured the levels of the key proinflammatory cytokines TNFα and IL-1β in the cortex of 5xFAD mice receiving currant-supplemented diet for 1, 3, and 6 months in comparison to normal diet and sugar-matched diet.