CDH1 and metastatic neoplasm: All recipient mice remained clinically well after an average of 100 d, but contained numerous ZSG+/Cdh1+/Icam1+ donor-cell clusters within their lungs, liver, kidneys and peritoneum at a frequency similar to metastatic tumors formed by tail-vein injections of tCZCs (Figs. 6e, 7g–i and Extended Data Fig. 6d).