In addition, significant upregulation was observed in DPPA5, DNM3OS, OR2T6, OR8H1 in four complications including neuropathy, ketoacidosis, hyperlipidemia and PCOs (p < 0.01) (Boxplots 8C, 8D, 8F,8H, respectively). The gene discussed is OR2T6; the disease is hyperlipidemia.