The inhibition of BMP2 signaling by LDN193189 or depletion of BMP2 by microRNAs are cytotoxicity in lung cancer cell line A549, but not immortal non-tumorigenic BEAS-2B bronchial epithelial cells27, suggesting that targeting BMP2 signaling may serve as a therapeutic strategy for treating lung cancers. This evidence concerns the gene BMP2 and lung cancer.