One study of early and advanced DKD cohorts indicated that the AUC value of the prognostic model for renal endpoint was 0.680 in clinical models alone, ranging from 0.709 to 0.735 in clinical models plus one biomarker (either urinary sTNFR1, TNFR2, or KIM1) and 0.752 in clinical models plus all three biomarkers22. Here, TNFRSF1B is linked to diabetic kidney disease.