HDAC9 and hydrops fetalis: A light but significant increase in global acetylation level of H3 in colonic mucosa of HF-fed mice compared to mice fed a standard diet (Chow diet) was observed (median Chow: 1.381 vs median HF: 1.918, p < .05), whereas no significant change in HDAC expression was noticed between the two groups of mice (Figure 5).