Consistent with prior findings of SOX2 being a key determinant of ZIKV infection (Zhu et al., 2020), the proportion of cells positive for SOX2 was higher in MR than HR GBM samples (Figure 2C; Figure S2E), whereas there was no significant difference in the fraction of cells labelled by the proliferation marker MKI67 (Figure S2F). This evidence concerns the gene SOX2 and Zika virus infectious disease.