SSTR2 and neuroendocrine carcinoma: To evaluate the translational potential of MMC(FNIR-Tag)-TOC,we first used the novel neuroendocrine carcinoma (NEC) patient-derivedxenograft (PDX) models, NEC913 (SSTR2+) and NEC1452 (SSTR2−),that more accurately recapitulate human disease34 (Figure 4A).