Whereas, the HF/HS group exhibited higher serum concentrations of IL-23 (P = 0.017), IL-10 (P = 0.046), IL-27 (P = 0.049), IL12p70 (P = 0.050) and IL-1β (P = 0.011) and a tendency for a higher IL-6 (P = 0.070) only at the late phase compared with the control mice (Fig 3H–3M). Here, IL27 is linked to hydrops fetalis.